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Study on the hypoglycemic effect of mango leaf extract grown in Son La

Published 06/27/2022

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How to Cite
Nguyen Duc Thanh, Hoang Thu Trang, Nguyen Thi Van Anh. "Study on the hypoglycemic effect of mango leaf extract grown in Son La". Vietnam Journal of Food Control. vol. 5, no. 2 (en), pp. 151-159, 2022

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Mango leaves were extracted by Soxhlet with 60% ethanol, the obtained solution was distilled to remove the solvent under reduced pressure. The results showed that when using the maximum allowable dose, there were no dead mice. Experimenting on blood glucose-lowering effects on diabetic white mice obtained the results: with a dose of 500 mg/kg giving the best therapeutic effect, even slightly better than the positive control drug gliclazide, the blood glucose level decreased immediately after three days. After 21 days reduced to 52.5% and brought the blood glucose index to normal. This is a new direction in the use of drugs of plant origin in general and Mango leaves in particular.


Mango leaves, diabetes, in vivo.


[1]. N. T. A. Lan et al., “Efficacy of young mango leaf extract (Mangifera indica L.) on diabetic rats,” The 7th National Scientific Conference on Ecology and Biological Resources, pp. 1290-1295, 2017.
[2]. N. Berardini, A. Schieber, I. Klaiber, U. Beifuss, R. Carle, and J.Conrad, “7-O-Methylcyanidin 3-O-β-D-Galactopyranoside, a novel Anthocyanin from Mango (Mangifera indica L. cv. ‘Tommy Atkins’) Peels”, Zeitschrift für Naturforschung (ISSN : 0932-0776), vol. 60, no. 7, pp. 801-804, 2005.
[3]. A. Bhowmik, L. A. Khan, M. Akhter, and B. Rokeya, “Studies on the antidiabetic effects of Mangifera indica stem-barks and leaves on nondiabetic type-1 and type-2 diabetic model rats,” Bangladesh Journal of Pharmacology, vol. 4, no. 2, pp. 110-114, 2009.
[4]. A. Sahrawat, S. Pal, and SK. Shahi, “Antibacterial activity of Mangifera indica (mango) leaves against drug resistant bacterial strains,” International Journal of Advanced Research, vol. 1, no. 6, pp. 82-86, 2013.
[5]. N. Wadood, N. Abmad, and A. Wadood, “Effect of Mangifera indica on blood glucose and total lipid levels of normal and alloxan diabetic rabbits,” Pakistan Journal of Medical Research, vol. 39, no. 4, pp. 142-145, 2000.