Bìa tạp chí

 

009bet

Assessment of potential hazards of the inadvertently present chemicals in food

Suvorov Dmitrii V. Zaitseva Nina V. Shur Pavel Z. Zelenkin Sergey E.
Published 10/04/2022

Article Details

How to Cite
Suvorov Dmitrii V., Zaitseva Nina V., Shur Pavel Z., Zelenkin Sergey E.. "Assessment of potential hazards of the inadvertently present chemicals in food". Vietnam Journal of Food Control. vol. 5, no. 4 (en), pp. 622-633, 2022
PP
622-633
Counter
360

Main Article Content

Abstract

During the 71st session of the Executive Committee of the Codex Alimentarius Commission, New Zealand proposed draft Guidelines for risk analysis of chemicals inadvertently present in food at low levels, noting that regulatory documents do not currently cover this group of substances. Methodological approaches to detecting and identifying chemical substances inadvertently present in foodstuffs were proposed In the Russian Federation. The developed methodological approaches include four stages: analytical identification of chemical substances; integrated assessment of chemical hazards employing additional selection criteria followed by the application of a score and summation of points; categorizing chemical substances with the assignment of potential hazard categories and final stage - health risk assessment for selected chemicals based on the integrated index. The presented methodological approaches were tested on the example of canned meat for infant nutrition consumed in the Russian Federation and the Socialist Republic of Vietnam. Nnitrosamines were assessed as a priority potentially hazardous inadvertently present chemical substance in samples of canned meat for infant nutrition for health risk assessment using methodological approaches developed in the Russian Federation. Assessment of the health risk to infants when consuming canned meat for infant nutrition containing Nnitrosamines on the example of products sold in the Russian Federation and the Socialist Republic of Vietnam revealed no excess hazard quotients (HQ < 1.0) in both territories. However, the calculation of carcinogenic risks has shown that when canned meat for infants sold in the Russian Federation from 6 months to 3 years of age is consumed, a carcinogenic risk may be formed in infants of the corresponding group. This difference between the Socialist Republic of Vietnam and the Russian Federation is due not only to the difference in the content of N-nitrosamines in the examined product but also to the greater volume of canned meat consumption in Russia.

Keywords:

nitrosamines, inadvertently present chemicals, contaminants, risk assessment.

References

[1]. Joint FAO/WHO Food Standards Programme, “Codex Committee On Contaminants In Foods. Eleventh Session. Rio de Janeiro, Brazil, 3–7 April 2017” [online]: https://www.fao.org/fao-who-codexalimentarius/sh-proxy/en/?lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FMeetings%252FCX-735-11%252FCRDs%252Fcf11_CRD27.pdf [Accessed 29/08/2022].
[2]. P. Carson, Hazardous Chemicals Handbook, 2nd ed. Oxford: Butterworth-Heinemann, 619 p, 2002.
[3]. American Conference of Governmental Industrial Hygienists, Inc., Documentation of the Threshold Limit Values and Biological Exposure Indices, 6th ed, Volumes I, II, III. Cincinnati: ACGIH, 1991, 1128 p.
[4]. “N-Nitrosodiethylamine. Material Safety Data Sheet” [online]: https://datasheets.scbt.com/sc-257861.pdf [Accessed 29/08/2022].
[5]. Toxicological profile for di-n-butyl phthalate. Washington: US Agency for Toxic Substances and Disease Registry, 225 p, 2001.
[6]. “Diethyl phthalate” [online]: https://pubchem.ncbi.nlm.nih.gov/compound/Diethylphthalate#section=Acute-Effects [Accessed 25/08/2022].
[7]. “Guidelines for the establishment and justification of hygienic standards for the content of chemical impurities, biological agents in food products according to risk criteria for human health” [online]: https://clck.ru/SHrRA [Accessed 25/08/2022].
[8]. Risk-based Food Inspection Manual, Rome: Food and Agriculture Organization of the United Nations, pp. 108, 2010.
[9]. Methodological Guidelines 4.1.3588-19 Measuring the content of N-nitrosamines (Ndimethyl-nitrosamine, N-methyl ethyl-nitrosamine, N-dipropyl-nitrosamine, Ndibutyl-nitrosamine, N-piperidine-nitrosamine) in food products (canned meat, mixed products containing meat and cereal) by chromatography-mass spectrometry. Moscow: Federal Service for Supervision of Consumer Rights Protection and Recovery of a Person, pp. 20, 2020.
[10]. “Agents Classified by the IARC Monographs, Volumes 1–132” [online]: https://monographs.iarc.who.int/agents-classified-by-the-iarc/ [Accessed 25/08/2022].
[11]. “Analysis of the actual consumption of food products by children under the age of three in the Russian Federation and the Socialist Republic of Vietnam for the purposes of health risk assessment,”in Actual directions and prospects of Russian-Vietnamese cooperation in the field of ensuring sanitary and epidemiological well-being: collective monograph, Volgograd: LLC "Publishing house "Volga-Press,” p. 367-375, 2019.
[12]. U.S. EPA, “Provisional Peer Reviewed Toxicity Values for N-Nitrosodimethylamine” [online]: https://cfpub.epa.gov/ncea/pprtv/documents/NitrosodimethylamineN.pdf [Accessed 25/08/2022].

 Submit