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Simultaneous determination of furan and its derivatives in food by headspace gas chromatography-mass spectrometry (HS-GC-MS)

Published 05/28/2021

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How to Cite
Nguyen Thi Ha Binh, Bui Cao Tien, Mai Thi Ngoc Anh, Pham Thi Hoai, Le Thi Hong Hao. "Simultaneous determination of furan and its derivatives in food by headspace gas chromatography-mass spectrometry (HS-GC-MS)". Vietnam Journal of Food Control. vol. 4, no. 3, pp. 182-189, 2021

Main Article Content


A method for the simultaneous determination of furans, 2-methylfuran and 3-methylfuran in some food by gas chromatography-mass spectrometry (GC-MS) has successfully developed. Analysed samples were treated by a headspace technique using furan-d4 as an internal standard. The detection limit of the method is 0.3 µg/kg, the quantitative limit of the method is 1.0 µg/kg. The recovery of the method is in the range of 72 to 110%. The relative standard deviation ranges from 3.3 to 13%. The method was applied to analyze 100 food samples, including: coffees, canned meats, baby foods, powdered milk. The results showed that furans, 2-methylfuran, 3-methylfuran were detected in 30 samples out of 100 collected samples. In particular, furans were found in a ranges of 5.7 to 2803 µg/kg in all of coffee samples, including instant coffee and roasted coffee. In addition, furans were detected in one baby food sample contains, furans and 2-methylfuran in four canned meat samples, and no furans milk were detected in powder sample among 25 analysed samples.


GC-MS, headspace, furan, 2-methylfuran, 3-methylfuran.


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